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Conversely, at least 5 days should be allowed after stopping Cymbalta before starting cymbalta an maoi intended to treat psychiatric cymbalta disorders see Contraindications china ( 4 ). At the highest 200 mg twice daily dose, the increase in mean pulse rate was.0.8 beats and increases in mean blood cymbalta pressure were.7.8 mm Hg (systolic) and.5 to 7 mm Hg (diastolic) up to 12 hours after dosing. An adequate airway, oxygenation, and ventilation should be assured, and cardiac rhythm and vital signs should be monitored. Serotonin syndrome symptoms may include mental status changes (e.g., agitation, hallucinations, delirium, and coma autonomic instability (e.g., tachycardia, labile blood pressure, dizziness, diaphoresis, flushing, hyperthermia neuromuscular symptoms (e.g., tremor, rigidity, myoclonus, hyperreflexia, incoordination seizures, and/or gastrointestinal symptoms (e.g., nausea, vomiting, diarrhea). What are the ingredients in Cymbalta? Such symptoms should be reported to the patient's prescriber or health professional, especially if they are severe, abrupt in onset, or were not part of the patient's presenting symptoms. Cymbalta demonstrated superiority over placebo as measured by greater china improvement in the Pediatric Anxiety Rating Scale (pars) for GAD severity score see Clinical Studies (.2 ). Activation of mania or hypomania has been reported in a small proportion of patients with mood disorders who were treated with other marketed drugs effective in the treatment of major depressive disorder. Do not use Cymbalta for a condition for which it was not prescribed. In most patients, the median time to detection of the transaminase elevation was about two months. Telephone numbers for certified poison control centers are listed in the Physicians' Desk Reference (PDR). 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